Bronopol CAS#52-51-7

Bronopol CAS#52-51-7

Effective Antimicrobial AgentBronopol acts as a preservative and biocide, preventing microbial growth in various formulations.


Versatile UsageIt can be incorporated into multiple products, including lubricants and cosmetic or pharmaceutical preparations.


Water-SolubleIts solubility in water allows easy formulation and dispersion in aqueous products.


Stability in FormulationsBronopol maintains antimicrobial efficacy over time, supporting long shelf-life of the products it protects.


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product description

Product Application of Bronopol CAS#52-51-7

Bronopol is a formaldehyde-releasing compound and has been identified as a potential allergen for dairy workers. In a reported case, bronopol contained in ultrasound lubricant jelly induced contact dermatitis in a veterinary surgeon.


Product Application of Bronopol CAS#52-51-7

Bronopol is used as an antimicrobial preservative at a concentration of 0.01–0.1% w/v, either alone or blended with other preservatives. It is applied in topical pharmaceuticals, cosmetics and personal care products, with a typical dosage of 0.02% w/v.

Parameters


Melting point130-133 °C(lit.)
Boiling point358.0±42.0 °C(Predicted)
density2.0002 (rough estimate)
refractive index1.6200 (estimate)
Fp167°C
storage temp.Inert atmosphere,Room Temperature
solubilityH2O: soluble100mg/mL, clear, colorless to faintly yellow
pka12.02±0.10(Predicted)
formCrystals or Crystalline Powder
colorWhite to yellow
Odorodorless
Water Solubility25 g/100 mL (22 ºC)
Merck141447
BRN1705868
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.
Major Applicationagriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
Cosmetics Ingredients FunctionsPRESERVATIVE
Cosmetic Ingredient Review (CIR)Bronopol (52-51-7)
InChI1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2
InChIKeyLVDKZNITIUWNER-UHFFFAOYSA-N
SMILESOCC(Br)(CO)[N+]([O-])=O
LogP1.150 (est)
CAS DataBase Reference52-51-7(CAS DataBase Reference)
NIST Chemistry ReferenceBronopol(52-51-7)
EPA Substance Registry SystemBronopol (52-51-7)


Safety Information


Hazard CodesXn,N
Risk Statements21/22-37/38-41-50
Safety Statements26-37/39-61-36/37/39
RIDADRUN 3241 4.1/PG 3
WGK Germany2
RTECSTY3385000
F4.2-8-9-21
TSCATSCA listed
HazardClass4.1
PackingGroupIII
HS Code29055999
Storage Class4.1B - Flammable solid hazardous materials
Hazard ClassificationsAcute Tox. 4 Dermal
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data52-51-7(Hazardous Substances Data)
ToxicityLD50 in mice, rats (mg/kg): 350, 400 orally (Croshaw)


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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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1. Why Supply Chain Transparency Matters in Global Chemical Procurement
Chemical buyers evaluate more than price and delivery time. Clear specifications, matching batch documents, consistent packaging information, and traceable logistics all affect customs clearance, warehouse inspection, and production use.
When selecting a supplier, buyers should review how the company confirms specifications, manages documents, handles changes, and responds to problems. Transparent processes help reduce order risks and improve long-term procurement reliability.


2. Seven Essential Details for a Chemical Product Inquiry
A product name alone is often insufficient for an accurate quotation. Buyers should provide the product name and CAS number, key specifications or purity, final application, required quantity, packaging requirements, destination, and expected delivery time or preferred Incoterms.
If COA, SDS, TDS, special labels, certifications, or registration documents are required, these details should also be included in the initial inquiry. Complete information helps suppliers confirm product, logistics, and documentation conditions more efficiently.


3. What Are the Differences Between COA, SDS, and TDS?
A COA is a batch-specific Certificate of Analysis showing test items, required ranges, and actual results. It is mainly used for quality verification and incoming inspection.
An SDS provides safety, handling, storage, emergency, and transportation information. A TDS describes typical product properties, technical parameters, and application guidance. Buyers should confirm the required document version, language, and applicable standards before placing an order.


4. Key Conditions to Confirm Before International Chemical Transportation
Before shipment, confirm the product identity, physical form, transport classification, and applicable regulations. An SDS is an important reference, but the final shipping arrangement must also meet regulatory and carrier requirements.
Packaging, sealing, moisture protection, palletizing, labels, ports, documents, Incoterms, and transport schedules should be clearly confirmed. Early verification helps prevent delays caused by carrier restrictions or incomplete documentation.


5. How to Evaluate Chemical Product Sample Test Results
Sample evaluation should consider both product compliance and application performance. Laboratory results do not always guarantee the same performance in every formulation or production process.
Before testing, record the sample batch, COA, storage condition, and sampling method. During application tests, keep consistent records of formulation, dosage, process conditions, and results. After approval, reconfirm the formal order specifications, inspection method, packaging, and batch documents.

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