Urea CAS#57-13-6

Urea CAS#57-13-6

Strong Hydrogen-Bonding Capability: Urea forms an extensive and stable hydrogen-bond network both in the solid state and in aqueous systems, enhancing its interaction with other molecules.


Excellent Water Solubility: Due to its strong affinity for hydrogen bonding with water, urea dissolves readily, enabling efficient use in aqueous formulations and processing systems.


Chemically Stable and Reactive Structure: The sp²-hybridized carbon and partial double-bond character of the C–N bonds provide structural stability while maintaining useful chemical reactivity.


High Functional Polarity: The relatively basic carbonyl oxygen enhances urea’s molecular polarity, improving compatibility and performance in chemical, agricultural, and industrial applications.


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product description

Product Description of Urea CAS#57-13-6

Urea displays state-dependent molecular geometry, adopting a planar configuration in the crystalline state but pyramidal nitrogen geometry in the gas-phase minimum-energy structure. In the solid phase, oxygen atoms form two N–H···O hydrogen bonds each, creating a stable hydrogen-bonding network that disrupts ideal packing and produces an open structure with ribbon-like arrangements and square cross-sectional channels. The sp²-hybridized central carbon imparts significant double-bond character to the C–N bonds, while the carbonyl oxygen shows greater basicity than in formaldehyde. Urea's high aqueous solubility arises from its strong hydrogen-bonding ability with water.


Product Application of Urea CAS#57-13-6

Urea is the primary nitrogen excretion product in mammals, synthesized in the liver from protein metabolism and eliminated in urine. It also occurs naturally in skin as an emollient with diuretic properties. In biochemistry, urea is widely used to denature proteins and solubilize insoluble protein species. It is particularly effective for renaturing proteins denatured with 6 M guanidine chloride, including inclusion bodies, and is often used in combination with guanidine hydrochloride and dithiothreitol to refold denatured proteins into their native conformations.

Parameters


Melting point

132-135 °C(lit.)

Boiling point

332.48°C (estimate)

density

1.335 g/mL at 25 °C(lit.)

vapor pressure

<0.1 hPa (20 °C)

refractive index

n20/D 1.40

storage temp

2-8°C

solubility

H2O: 8 M at 20 °C

form

powder

pka

0.10(at 25℃)

color

white

Specific Gravity

1.335

Odor

almost odorless

PH

8.0-10.0 (20℃, 8M in H2O)

Water Solubility

1080 g/L (20 ºC)

λmax

λ: 260 nm Amax: 0.03λ: 280 nm Amax: 0.02

Merck

14,9867

BRN

635724

Dielectric constant

3.5(Ambient)

Stability

Substances to be avoided include strong oxidizing agents. Protect from moisture.

InChIKey

XSQUKJJJFZCRTK-UHFFFAOYSA-N

LogP

-1.660 (est)

CAS DataBase Reference

57-13-6(CAS DataBase Reference)

NIST Chemistry Reference

Urea(57-13-6)

EPA Substance Registry System

Urea (57-13-6)


Safety Information


Hazard Codes

Xn,Xi

Risk Statements

36/37/38-40-38

Safety Statements

26-36-24/25-37

RIDADR

Not regulated

WGK Germany

1

RTECS

YR6250000

TSCA

Yes

HS Code

31021010

Hazardous Substances Data

57-13-6(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 8471 mg/kg LD50 dermal Rat 8200 mg/kg


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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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