Dexamethasone CAS#50-02-2

Dexamethasone CAS#50-02-2

Potent Anti-Inflammatory Effects:Dexamethasone effectively reduces and inhibits inflammation, providing relief from inflammatory symptoms.


Anti-Toxic and Anti-Allergic PropertiesThe drug exhibits strong anti-toxic and anti-allergic actions, helping to manage allergic reactions and toxic responses.


Synergistic Clinical UseDexamethasone is most effective when used in combination with other medications, enhancing the overall therapeutic outcome.


Widely Used in Clinical PracticeIt is a commonly applied drug in medical settings, trusted for its reliable ability to manage inflammatory and allergic manifestations.



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product description

Product Description of Dexamethasone CAS#50-02-2

Dexamethasone is a widely used drug in clinical practice, frequently administered alongside other medications. It possesses anti-inflammatory, anti-toxic, and anti-allergic properties. However, it does not treat the underlying disease and only serves to reduce or suppress the symptoms of inflammation. Therefore, careful consideration is required during clinical use. It is generally not used alone and is most effective when combined with other drugs.


Product Application of Dexamethasone CAS#50-02-2

Dexamethasone (dexamethasone sodium phosphate EP impurity A) is a glucocorticoid widely used for its anti-inflammatory properties. It regulates the survival, growth, and differentiation of T cells and inhibits the induction of nitric oxide synthase.

This drug is primarily applied for anti-inflammatory and anti-allergic purposes and is suitable for treating rheumatoid arthritis and other collagen-related diseases.


Parameters


Melting point262-264 °C (lit.)
alpha75 º (c=1, dioxane)
Boiling point568.2±50.0 °C(Predicted)
density1.1283 (estimate)
refractive index76 ° (C=1, Dioxane)
Fp9℃
storage temp.2-8°C
solubilityethanol: 1 mg/mL
formpowder
pka12.13±0.70(Predicted)
coloroff-white
biological sourcesynthetic (organic)
Water Solubility10 mg/100 mL (25 ºC)
SensitiveLight Sensitive
Merck142943
BRN2066651
BCS Class1 (CLogP), 3 (LogP)
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.
InChIKeyUREBDLICKHMUKA-CXSFZGCWSA-N
CAS DataBase Reference50-02-2(CAS DataBase Reference)
NIST Chemistry ReferencePrednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2)
EPA Substance Registry SystemDexamethasone (50-02-2)


Safety Information


Hazard CodesXi,Xn,T,F
Risk Statements43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11
Safety Statements36/37-45-36-26-22-16
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany2
RTECSTU3980000
TSCAYes
HS Code29372210
Hazardous Substances Data50-02-2(Hazardous Substances Data)
ToxicityLD50 oral in rat: > 3gm/kg


Safety Information


Hazard CodesXi,Xn,T,F
Risk Statements43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11
Safety Statements36/37-45-36-26-22-16
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany2
RTECSTU3980000
TSCAYes
HS Code29372210
Hazardous Substances Data50-02-2(Hazardous Substances Data)
ToxicityLD50 oral in rat: > 3gm/kg



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